Медицинский советник, Биолог исследователь (Drug development), Менеджер медицинских проектов

Analysis of public data on diseases and their subtypes (publications, grants, patents, clinical trials, reports of biotechnological companies), creation of molecular maps describing the mechanisms of diseases Analysis of the main triggers of signaling cascades associated with human diseases, search for potential regulators, biomarkers and targets for diseases. Interpretation of the results of bioinformatics analysis of OMICS data, selection and substantiation of hypotheses on molecular targets and biomarkers of diseases Analysis of various evidence of the association of genes and diseases (mutations, GWAS associations, data on knockouts / knockdowns in model organisms and cell lines), analysis of the possibility of using the selected gene as a target Regular presentation of the work results, writing reports, scientific articles on the work results

Developing in vitro and in vivo transgenic models of human diseases, and in particular physiological models for human lung cancer resulting in RUB 15 000,000 in lab grant funding from Russian Science Foundation Evaluation of the potential defensive strategy against Influenza A in transgenic chicken cell line models Developing technological pipelines for the efficient genome editing of primary stem cells and animal embryos using CRISPR/Cas9 technology Managed laboratory functions including organization, drafting of regulatory documents, ordering reagents, supplies, and equipment Demonstrated effective leadership by managing and supervising research activities of postdoctoral trainees and undergraduate students

Identified a new HSP90 drug conjugate in small cell lung cancer resulting in publications and leading to a number of successful collaborations in academia and industry. Identified new prognostic markers for squamous cell carcinoma of head and neck (SCCHN) and epithelial ovarian cancer (EOC), by exploring networks of genes that influenced the DNA damage response resulting in multiple publications. Reprobated the targeted cancer therapies for autosomal dominant polycystic kidney disease (ADPKD): performed preclinical testing of several inhibitors (erlotinib, alisertib, ganetespib) on murine Pkd1-conditional knockout model

Изучение молекулярно-генетических нарушений в гастроинтестинальных стромальных опухолях (ГИСТ). Молекулярно-генетическая диагностика опухолей. Результаты исследований были представлены на многих зарубежных и российских конференциях.